India will have to make a choice between the uncapped Anshul Kamboj and Prasidh Krishna, with Akash Deep ruled out of the 4th Test against England.
The visitors were already depleted by injuries to Arshdeep Singh, who had been sidelined from the Manchester Test, and Nitish Kumar Reddy who had been ruled out of the rest of the series.
Captain Shubman Gill confirmed that Akash Deep will also miss the fourth Test at Old Trafford because of a groin niggle.
Uncapped Haryana pacer Anshul Kamboj, who was added to the squad as cover, is "very close to making his debut" as third seamer, with India's team management set to make a call between him and Prasidh Krishna on Wednesday morning.
India, however, will be bolstered by the return of their spearhead Jasprit Bumrah.